Objective To investigate the comparability of the two kinds of serum Her-2/neu protein detection reagent and provide experimental data for choosing reasonable detection method and reagent. Methods Serum samples from 195 cases of breast cancer group, 60 cases of healthy control group and 100 cases of other tumor patients group were detected by Simens chemiluminescence immunoassay (CLIA) and DRG ELISA methods respectively. Results The detection results of 351samples in all 355 samples were consistent with two reagents and the total coincidence rate was 98.87%. The correlation coefficient r was 0.9919 between the two groups of detection results (P=0.000). All the Her-2/neu protein results in patients other tumor and healthy controls were lower than that of cutoff value. Conclusion The two kinds of serum Her-2/neu protein detection reagent are comparable, and the CLIA might be a good selection for clinical practice.
LI Xue-xiang
,
WANG Min-jie
,
HAN Bin-bin
,
HAN Xiao-hong
,
QI Jun
. Comparative Study on the Two Detecting Reagents of Serum Her-2/neu[J]. Labeled Immunoassays and Clinical Medicine, 2013
, 20(3)
: 176
-178
.
DOI: 10.11748/bjmy.issn.1006-1703.2013.03.017
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