Objective To explore the correlation between serum levels of Cystatin C and Glutamyl transferase (GGT) in patients with chronic kidney disease (CKD). Methods Patients with chronic kidney disease were divided into CKD stage 1(36cases), CKD stage 2 (39 cases), CKD stage 3 (36cases), CKD stage 4 (20 cases) and CKD stage 5 (24 cases) groups according to K/DOQI. The serum levels of CysC,GGT and Cr in each group and 45 healthy people (control group) were detected. Results The serum levels of CysC and GGT in patients were significantly higher that of control group (P＜0.01). There was no significantly difference in patients for serum GGT levels at different stages (P＞0.05). The serum CysC and Cr levels were increased as the kidney lesion become worse, and there was a positive correlation between the serum Cys C and Cr (r=0.9980). Conclusion The serum CysC is a sensitive indicator for early glomerular filtration faction, and might be a very valuable in assessing the kidney lesion stage and monitoring therapy effects.
LIU Ji-yong, QIAN Cheng-rong, WANG Jian-jun, DING Jun-li, ZHAO Yong,ZHOU Zhi-wei YIN Guang-yue
. The Serum Levels of Cystatin C and Glutamyl Transferase in DifferentStages of Chronic Kidney Disease[J]. Labeled Immunoassays and Clinical Medicine, 2013
, 20(3)
: 148
-150
.
DOI: 10.11748/bjmy.issn.1006-1703.2013.03.008
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