Objective To identify clinical infection distribution and antibiotic resistance spectrum of Acinetobacter baumannii, and to guide effective clinical prevention and rational drug use.Methods The 254 Acinetobacter baumannii strains clinically isolated from the year of 2009 to 2011were investigated by drug susceptibility using the disk diffusion method, and the results were statistically analyzed by WHONET 5.5.Results The 254 Acinetobacter baumannii isolates were mostly in sputum specimens, andthe ratios were about 90.5%. The resistance rates to piperacillin and ceftriaxone were 79.38% and 89.33% respectively. The antibiotic resistance rates of ceftazidime, cefepime, amikacin, tobramycin, and two different types of plus β-lactamase inhibitor compound were about 51%-57%. Polymyxin B and cefoperazone / sulbactam had strong antibacterial activity, and the resistance rates were 0.63% and 17.88%.Conclusion Acinetobacter baumannii is a domain opportunistic pathogen in hospital infection with high multiple drug resistance. It should be widespread emphasized with clinical regimen of antibiotic use in order to prevent further spread of the drug resistance within hospital.
CHEN Yong-de
,
YAN Chen-ying
,
DONG Guo-wei
,
TANG Xin-ning
,
ZHANG Ying-xin
,
GUO Hai-yi
,
GUO Jie
. Distribution and Drug Resistance of Acinetobacter Baumannii[J]. Labeled Immunoassays and Clinical Medicine, 2013
, 20(2)
: 99
-100
.
DOI: 10.11748/bjmy.issn.1006-1703.2013.02.013
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