Objective To explore the value of urine β2-MG detection in early renal damage of H type hypertension. Methods The serum Hcy and urine β2-MG in 67 case of H type hypertension patients were detected with enzymatic cycling method and radio immunoassay. Results The serum Hcy and urine β2-MG in H type hypertension patients were significantly increased (P<0.01). Conclusion The detection of urine β2-MG has important value in diagnosis of early renal damage with H type hypertension.
SHI Jin
,
RONG Rong
,
WEN Qing-xiang
. Clinical Value of β2-Microglobulin Detection in Early Renal Damageof H Type Hypertension[J]. Labeled Immunoassays and Clinical Medicine, 2013
, 20(2)
: 69
-70
.
DOI: 10.11748/bjmy.issn.1006-1703.2013.02.002
[1] 张琛涛,新玲.H型高血压的研究进展[J].中国医药指南,2011,9(26):202-203.
[2] Moustapha A, Naso A, Nahlawi M, et al. Prospective study of hyperhomocysteinemia as an adverse cardiovascular risk factor in end stage renal disease[J].Circulation, 1998,97(2):138-141.
[3] 曹国良,乔永芳,戴蓉芳,等.中美欧指南之比较[J].医学与哲学,2005,2(5):46-47.
[4] 崔征,杨志娜,田卫东,等.监测血清同型半胱氨酸和β2-微球蛋白在糖尿病肾病患者早期肾损伤中的诊断价值[J].中国疗养医学,2010,19(11):1035-1036.
[5] Henning B F,Riezler R, Tepel M,et al. Evidence of altered homocysteine metabolism in chronic renal failure[J].Nephron,1999,83(4):314-322.
[6] Pema A F,Ingrosso D, Satta E,et al. Metabolic consequences of hyperhomocysteinemia in uremia[J]. Am J Kidney Dis, 2001,38(4 Suppl 1):S85-90.