Objective To investigate the clinical significance of ischemia modified albumin (IMA) in the diagnosis of patients with acute chest pain. Methods Among the 125 patients with chest pain who were hospitalized in our department, 32 were grouped into non-coronary heart disease (NCAD) group, 21into unstable angina (UAP) group and 72 into acute myocardial infarction (AMI) group. Blood sample were drown at entry, 8 hours and 24 hours after last attacking, and the levels of IMA, cTnI and MYO were determined. Statistical analysis was done by SPSS 13.0 statistical package. Results The levels of IMA at entry and 8 hour after last attacking in NCAD group were significantly different compared to the other groups (P＜0.05), but the difference was not statistically significant at 24 hour after last attacking (P＞0.05). 92 patients in total 125 patients were diagnosed as the acute coronary syndrome (ACS). The diagnostic sensitivity of IMA (82.6%) was higher than that of electrocardiogram (29.7), cTnI (42.8%) and MYO (64.3%). The heart source diseases immediate diagnosis positive rates of different judgment target combinations were from 85.2% to 93.6%. Conclusion IMA might have an important value in the early diagnosis of patients with acute chest pain.
YU Qi
,
NIU Wei-xi
,
TANG Fa-kuan
,
HUA Ning
,
LIN Le-jian
. Clinical significance of Ischemia Modified Albumin in the EarlyDiagnosis of Patients with Acute Chest Pain[J]. Labeled Immunoassays and Clinical Medicine, 2013
, 20(1)
: 4
-6
.
DOI: 10.11748/bjmy.issn.1006-1703.2013.01.002
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