Objective To evaluate the efficacy of the transfusion of pre-stored apheresis autologous red blood cell in retroperitoneal tumor elective surgery. Methods 20 patients in our hospital from January 1 to November 30 in 2014 who were underwent transfusion of pre-stored pheresis autologous red blood cell for retroperitoneal tumor elective surgery were retrospectively analyzed. Results The routine blood indicators of 20 patients after apheresis blood collection were decreased, but the PLT, Hct, Hb were maintained at a higher level (PLT > 150×109/L, Hct>30%, Hb>110 g/L). The autologous transfusion did not cause coagulation dysfunction and tissue hypoxia. After transfusing autologous blood，the indicators become higher than that of preoperation, which could prevent the occurrence blood loss anemia. Conclusion Pre-storage type of autologous blood transfusion is an effective and safe method .It not only can solve the requirements for big elective surgery but also can effectively reduce the adverse transfusion reactions.