Abstract：Objective To explore the clinical curative effects of the treatment of keloids with 90Sr radiation and to choose adaptive indications by Vancouver scale. Methods 105 patients with 131 keloids were involved in this study. These keloids scored by VSS in color and luster, thickness, vascularity, softness and were divided into two groups (Group A 0～8, Group B 9～15 ). The patients were followed up for 6 to 12 months after the treatment with 90Sr radiation for efficacy evaluation. Results The cure rate of 131 keloids was 48.09%, and the improve rate was 51.91%, and the total effective rate was 51.91%. The radiation dose in Group A was 23.5±8.2Gy, and the cure rate was 62.69%, the adverse effect rate was 16.42%. The radiation dose in Group B was 35.1±6.2Gy, and the cure rate was 32.81%, the adverse effect rate was 48.48%. Conclusion Vancouver scale is a simple, effect and accurate method to select the appropriate keloid patients for 90Sr applicator therapy.