Objective To provide scientific evidence for continuous improvement of Digoxin plasma concentration critical value system. Methods Digoxin plasma concentration critical value was screened out from laboratory information system. The occurrence rate of Digoxin plasma concentration critical value, and its daily distribution, weekly distribution and department distribution were calculated to evaluate the range and turnaround time for critical value. Results The occurrence rate of Digoxin plasma concentration critical value was found to be 2.98%. From the perspective of department, the majority critical value was from the department of cardiology. After the evaluation of distribution diagram of Digoxin plasma concentration critical value range and coincidence rate, the critical value of digoxin could continue to be used. The laboratory turnaround time for 83.3% critical value was less than three hours. Conclusion Regular evaluation and continuous improvement of Digoxin plasma concentration critical value report procedures may help to improve work efficiency for better meet patients' safety needs.