Objective To make specialized nurses play a better role in nursing counseling and guidance, and to ensure the continuity of care for tumor patients. Materials We compared specialized nurses with normal nurses by health education, compliance of the patient, nurse operating and wound care with a questionnaire. Specialized nurses participated in tumor multidisciplinary consultation twice a week in 100 patients. It was helped to improve clinical nursing standards of specialized nurses. Results 96% of doctors and 78% of patients and their relatives thought it was effective. Conclusion Specialized nurses with high levels of patients and their relatives’ satisfaction. Specialized nurses participating in tumor multidisciplinary consultation could effectively improve specialized nursing quality, put forward nursing diagnosis, consummate the rules and regulations, improve duty of work, flow of work, and content of work, enhance patients’ relatives satisfaction, continuing multiply the impact of specialized nurses.