Objective To investigate the value of abnormal suggestion in the scatter diagram of blood cell analyzer to the diagnosis of hematological diseases. Methods 130 cases of outpatients were included in our study. The scatter diagram, abnormal cell distributions and disease suggestions of blood cell analyzer and the results of microscopic analyze of blood sample were systematically analyzed. Results The coincidence rate of abnormal cell distributions or disease suggestions and clinical diagnosis were relatively high in the venous blood sample. While the coincidence rate were comparatively lower when using finger blood samples. In this occasion, microscopic analyze of blood sample were also needed. Conclusion It is important to observe the abnormal cell distributions and disease suggestions in the scatter diagram of blood cell analyzer seriously. It can be used to assist making the correct diagnosis of leukemia.