Abstract: Objective To explore the comparability of the AST results analyzed on two biochemistry analyzers and verified through range test. Methods According to the range test comparability scheme, two samples of different AST concentration were selected and analyzed respectively on two biochemistry analyzers to assess the comparability of the detection systems. Results Based on the evaluation standards of the comparable biological variability, the range value obtained by the two detection systems was under acceptable criteria. Conclusion The AST results analyzed by the two detection systems were absolutely comparable, and the range test comparability scheme is simple and eminently practical.