Abstract : Objective To explore the clinical values of Cystatin C (Cys C) and renal dynamic imaging in renal function damage. Methods The serum Cys C and Cr levels and renal dynamic imaging in 52 random patients in our hospital were analyzed. Results The renal dynamic imaging decreases with the increase of renal function damage, and the concentration of serum Cys C level was increased with the increase of renal function damage. Conclusion The combined detection of serum Cys C and renal dynamic imaging could help to understand the changes of glomerular filtration rate, and it may be used as reliable index to evaluate the renal function damage.