Objective To explore the susceptibility of Enterococcus faecium and Enterococcus faecalis isolated from clinical species and provide data for anti-infection therapy. Methods The identification and drug susceptibility of clinical isolates was carried out by using the VITEK2 Compact system, and the results were determined based on the interpretation of CLSI 2012 break point. Results Most of the Enterococcus faecium and Enterococcus faecalis isolated from urine (48.92%) and blood (12.99%). Enterococcus faecalis isolated from different speciemens didn’t have statistical difference from Enterococcus faecium. No strains of vancomycin-, linezolid- and tigecycline-resistant Enterococcus faecium and Enterococcus faecalis were detected. The susceptibility rates of Enterococcus faecium to quinupristin-dalfopristin and tetracycline were higher than that of Enterococcus faecalis. And the susceptibility rates of Enterococcus faecium to nitrofurantoin, ampicillin, penicillin, moxifloxacin, levofloxacin and ciprofloxacin were lower than that of Enterococcus faecalis. Conclusion The drug susceptibility of Enterococcus faecium and Enterococcus faecalis is different. Doctors should choose the proper therapy based on difference of their drug resistance among Enterococcus faecium and Enterococcus faecalis. At present, vancomycin, linezolid and tigecycline are the best choice for treatment against the infection caused by Enterococcus faecium and Enterococcus faecalis.
熊 杰,邹自英,朱 冰,曾 平,谭积善
. Susceptibility Analysis of Enterococcus Faecium and Enterococcus Faecalis Strains[J]. Labeled Immunoassays and Clinical Medicine, 2013
, 20(5)
: 319
-321
.
DOI: 10.11748/bjmy.issn.1006-1703.2013.05.013