目的探讨吸烟量对高血压患者血总胆固醇(TC)、总甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)的影响，为冠心病的防治提供依据。方法采用流行病学问卷调查表的形式，没有吸烟史的高血压患者99例和有吸烟史的高血压患者105例，并按吸烟史的情况进行调查，按吸烟量分为吸烟0、1、2、3级。对比分析4个等级组四项血脂水平。结果吸烟1、2、3级TC、TG、LDL水平显著高于吸烟0级(P＜0.01)，吸烟3级HDL显著低于吸烟0级(P＜0.01)。结论吸烟与高脂血症有密切关系，是高血压病的危险因素之一，吸烟可影响高血压病的防治。
Objective To investigate the influence of cigarette smoking amount on the blood lipid level in patients with hypertension and to provide the basis for CHD prevention and treatment. Methods 204 of volunteers including 105 smokers and 99 non-smokers were selected to be investigated their smoking history by epidemiological questionnaire. They were divided into 4 groups according to the amount of smoking cigarettes (Group 0: non-smoking; Group 1: <100 cigarettes per year; Group 2: <200cigarettes per year; and Group 3: >200 Cigarettes per year). The level of blood lipids in patients with hypertension and controls were detected. Results The blood levels of TC, TG, and LDL in group 1to 3 were significantly higher than thatin group 0 (P＜0.01). The level of HDL in group 3 was significantly lower than in group 0 (P＜0.01). Conclusion Smoking is one of the risk factor leading to abnormality of blood lipid and may result in hypertension. The cigarette smoking may affect the prevention and cure to hypertension.
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