[1] Parkin D M. Global cancer statistics2002 [J].CA Cancer J Clin, 2005,55(2): 74-108.
[2] Arru M.Analysis of prognostic factors influencing long-term survival after hepatic resection for metastatic colorectal cancer [J].World J Surg, 2008,32(1): 93-103.
[3] Taniai N. Surgical treatment for better prognosis of patients with liver metastases from colorectal cancer [J].Hepatogastroenterology, 2007,54(78): 1805-1809.
[4] Chambers A, F Matrisian. Changing views of the role of matrix metalloproteinases in metastasis [J].J Natl Cancer Inst, 1997,89(17): 1260-1270.
[5] Kawada K,Hasegawa S, Murakami T,et al. Molecular mechanisms of liver metastasis [J].Int J Clin Oncol, 2011,16(5): 464-572.
[6] Voisin T.Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases: an openable gate to apoptosis [J].Cancer Res, 2011,71(9): 3341-3351.
[7] Papavasiliou P. Circulating tumor cells in patients undergoing surgery for hepatic metastases from colorectal cancer [J].Proc (Bayl Univ Med Cent), 2010,23(1): 11-14.
[8] Katsuno H. Does the presence of circulating tumor cells in the venous drainage of curative colorectal cancer resections determine prognosis? A meta-analysis [J].Ann Surg Oncol, 2008,15(11): 3083-3091.
[9] Cohen S J. Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer [J].Ann Oncol, 2009,20(7): 1223-1229.
[10]Koch M. Detection of disseminated tumor cells in liver biopsies of colorectal cancer patients is not associated with a worse prognosis [J].Ann Surg Oncol, 2007,14(2): 810-817.
[11] Shimada R. Prognostic significance of CTCs and CSCs of tumor drainage vein blood in Dukes’ stage B and C colorectal cancer patients[J].Oncol Rep, 2012,27(4): 947-953.
[12] Gangopadhyay A, DA Lazure, P Thomas, et al.Adhesion of colorectal carcinoma cells to the endothelium is mediated by cytokines from CEA stimulated Kupffer cells [J].Clin Exp Metastasis, 1998,16(8): 703-712.
[13] Aarons C B. Carcinoembryonic antigen-stimulated THP-1 macrophages activate endothelial cells and increase cell-cell adhesion of colorectal cancer cells [J].Clin Exp Metastasis, 2007,24(3): 201-209.
[14] Kanellos I. Value of carcinoembryonic antigen assay in predicting hepatic metastases, local recurrence, and survival after curative resection of colorectal cancer [J].Surg Today, 2006,36(10): 879-884.
[15] Kutun S. Carcinoembryonic antigen to detect hepatic metastases of colorectal cancers [J].Surg Today, 2003,33(8): 590-594.
[16] Wang Y. Prognosis of colorectal cancer with liver metastasis: value of a prognostic index [J].Braz J Med Biol Res, 2010, 43(11): 1116-1122.
[17] Fang Y J. Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer [J].Int J Colorectal Dis, 2009, 24(8): 875-884.
[18] Zucker S. Measurement of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues.Clinical and experimental applications[J]. Ann N Y Acad Sci, 1999. 878: 212-227.
[19] Schoppmann A. Comparison of lymphangiogenesis between primary colorectal cancer and corresponding liver metastases [J]. Anticancer Res, 2011, 31(12): 4605-4611.
[20] Kobayashi H. Messenger RNA expression of COX-2 and angiogenic factors in primary colorectal cancer and corresponding liver metastasis [J].Int J Oncol, 2009, 34(4): 1147-1153.
[21] Kaio E. Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma [J].Oncology, 2003, 64(1): 61-73.
[22] Yarom N. EGFR expression variance in paired colorectal cancer primary and metastatic tumors [J].Cancer Biol Ther, 2010, 10(5): 416-421.
[23] Radinsky R.Modulation of tumor cell gene expression and phenotype by the organ-specific metastatic environment [J].Cancer Metastasis Rev, 1995, 14(4): 323-338.
[24] Crowe P J. Genetic markers of survival and liver recurrence after resection of liver metastases from colorectal cancer [J].World J Surg, 2001, 25(8): 996-1001.
[25] Molinari F. Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant [J].Br J Cancer, 2009, 100(7): 1087-1094.
[26] Barozzi C. Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel [J]. Cancer, 2002, 94(3): 647-657.
