目的分析雅培化学发光法在HIV筛查试验中的假阳性。方法对本院2011年8月至2012年3月期间所有术前检查病人通过雅培化学发光法进行HIV筛查试验检测。结果39076例病人血清标本中，共筛检出阳性血清31例，经北京市疾病控制中心通过免疫印迹法(WB)进行确认后，21例为阳性，6例为不确定，4例为阴性。结论雅培化学发光法HIV抗原抗体联合检测假阳性率(12.90%)较高，因此仍应结合临床资料及确认试验结果综合判断。
Objective To evaluate the false-positive of Abbott chemiluminescence immunoassay (CLIA) in HIV screening test. Methods The total 39076 samples from the pre-operation patients (from August 2011to March 2012) in Beijing Tongren Hospital were tested for HIV screening through the ARCHITECT I2000. Results 31samples were screened as the anti-HIV positive.After the HIV confirmation test by Beijing Center for Disease Control, 21samples were diagnosed as the anti-HIV positive, 6 samples were indeterminate and 4 samples were anti-HIV negative. Conclusion The false-positive rate of ARCHITECT HIV Ag/Ab Combo is high(12.90%), the anti-HIV positive should be diagnosed based on clinical data and HIV confirmation test with regular follow-up.
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