摘要：目的 探讨可作为预测增殖性糖尿病性视网膜病的危险因素。方法 选取2011年5月至2013年11月间在我院眼科怀疑为糖尿病视网膜病变患者168例作为研究对象，空腹抽取静脉血，送检验科实验室检测EPO、糖化血红蛋白、FBS、CRP水平、血脂、载脂蛋白A和B。采用t检验和χ2检验、多因素logistic回归分析确定增殖性糖尿病性视网膜病发生的独立危险因素。结果 在怀疑为糖尿病视网膜病变患者168例中，测得患增殖性糖尿病性视网膜病患者28例，通过计算得出患者中增殖性糖尿病性视网膜病的患病率为16.67%。为了探讨PDR的危险因素，我们将全部PDR患者的可能危险因素纳入多因素logistic回归分析。结果表明，EPO（OR=0.31，95％CI：0.04~0.95，P=0.042）是预测增殖性糖尿病性视网膜病的独立危险因素。结论 血浆促红细胞生成素可作为预测增殖性糖尿病性视网膜病的危险因素。

Abstract: Objective To study the plasma erythropoietin used as a factor to predict the risk of proliferative diabetic retinopathy. Methods 168 suspected diabetic retinopathy patients were selected as the research object. The levels of EPO, glycosylated hemoglobin, FBS, CRP, serum lipid, apolipoprotein A and B in patients were detected. The t test, χ2 test and multiple factor analysis were used to identify the independent risk factors of proliferative diabetic retinopathy. Results 28 cases among 168 suspected diabetic retinopathy patients were confirmed as proliferative diabetic retinopathy patients, the prevalence rate was 16.67%. The multiple factors logistic regression analysis results showed that EPO was an independent risk factor for predicting of proliferative diabetic retinopathy. Conclusion Plasma erythropoietin could be used one of factors for predicting the risk of proliferative diabetic retinopathy.