摘要： 目的 探讨血清非高密度脂蛋白胆固醇(non-HDL-C)水平在急性脑梗死(ACI)患者中的临床意义。 方法 收集ACI组96例,对照组98例, 各组均测定血清总胆固醇(TC)、甘油三脂(TG) 、高密度脂蛋白(HDL-C)和低密度脂蛋白( LDL-C) 、载脂蛋白B （APOB），并计算出非高密度脂蛋白胆固醇(non-HDL-C)。 结果 ACI组non-HDL-C、APOB 、TC、TG、LDL-C水平明显高于正常对照组, HDL-水平显著低于对照组，各组间差异均有统计学意义(P<0.05),non-HDL-C与APOB、TC、TG、LDL-C 呈正相关，与HDL-C呈负相关。 结论 non-HDL-C可作为评价ACI危险程度的指标之一，应重视ACI和ACI高危人群血清non-HDL-C水平的检测。

Abstract: Objective To explore the clinical value of serum Non-HDL-C level in acute cerebral infraction (ACI) patients. Methods The serum levels of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and apolipoprotein B (apoB) in 96 cases of ACI patients and 98 health controls were detected and non-HDL-C level was calculated. Results Compared with health controls, ACI group had significantly higher level in serum non-HDL-C, apoB, TC, TG, LDL-C and lower HDL-C levels (p<0.05). The serum Non-HDL-C level was positively correlated with apoB, TC, TG and LDL-C, and negatively correlated with HDL-C. Conclusion The serum non-HDL-C levels is associated with ACI and might be as high risks index in the evaluation of ACI.