摘要： 目的 探讨联合抗菌药物对社区获得性肺炎患者CRP、PCT的影响及疗效。方法 180例社区获得性肺炎患者随机分为治疗组和对照组，对照组予抗菌药物加常规对症治疗，治疗组在此几乎上予痰热清治疗，比较两组临床疗效，细菌清除率，以及PCT、CRP水平的变化情况和不良反应发生情况。结果 治疗组总有效84例，有效率达93.3%，明显高于对照组（81.1%）（P<0.05）。治疗组细菌清除率为94.0%，高于对照组（82.3%）（P<0.05）。与治疗前比较，治疗后两组CRP、PCT均降低（P<0.05）。而治疗后治疗组CRP、PCT水平均低于对照组（P<0.05）。两组不良反应发生率差异无统计学意义（P>0.05）。结论  痰热清联合抗菌药物对CAP具有较高的疗效和安全性，并且可以降低CAP患者CRP、PCT水平。

Abstract：Objective To investigate the effect of combined Tanreqing injection with antibiotics on C-reactive protein (CRP) and procalcitonin (PCT) in community acquired pneumonia patients. Methods 180 cases of community acquired pneumonia were randomly divided into treatment group and control group. Patients in control group were treated with antibiotics plus conventional symptomatic treatment, and patients in treatment group were treated with Tanreqing injection. The serum levels of PCT and CRP in patients were detected. The comparison of clinical efficacy, bacterial clearance rate, and the changes of PCT and CRP levels and adverse reactions occur. In two groups were analyzed. Results The total effective rate in treatment group (93.3%) was significantly higher than that of the control group (81.1%) (P<0.05). The bacterial clearance rate of the treatment group (94%) was higher than that of control group (82.3%) (P<0.05). The levels of PCT and CRP in both groups after treatment were decreased compared with that of before treatment (P<0.05). The levels of PCT and CRP in the treatment group after treatment were lower than those in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion The Combined Tanreqing injection with antibacterial drugs could have high efficacy and safety, and reduce the level of PCT and CRP in patients with community acquired pneumonia.