摘要：目的 研究慢性丙型肝炎患者甲状腺功能与肝功能指标的关系。方法 收集196例慢性丙型肝炎患者，检测甲状腺功能及肝功能相关指标，并对甲状腺功能和肝功能的关系进行分析。结果 196例慢性丙型肝炎患者中38例存在甲状腺功能异常，其中2例为甲状腺功能亢进，3例为甲状腺功能减退，33例为亚临床甲状腺功能减退。血清谷丙转氨酶（ALT）、谷草转氨酶（AST）、总蛋白（TP）、白蛋白（ALB）、球蛋白（GLO）水平在甲状腺功能正常组与甲状腺功能异常组中差异无统计学意义（P>0.05）；肝功能相关指标不是甲状腺功能异常的危险因素（P>0.05）。结论 19.4%慢性丙型肝炎患者存在甲状腺功能的异常，明显高于正常人群；肝功能水平对甲状腺功能异常无明显影响。

Abstract: Objective To investigate the relationship of thyroid function and liver function in patients with chronic hepatitis C. Methods The levels of thyroid hormone and liver function in 196 cases of HCV patients were detected. The relationship of them was analyzed. Results In 196 patients of HCV, there were 38 cases suffered from thyroid dysfunction, 2 of them were hyperthyroidism, 3 of them were hypothyroidism, and 33 of them were subclinical hypothyroidism. The levels of ALT, AST, TP, ALB and GLO in normal thyroid function had no significant differences with that of thyroid dysfunction group（P>0.05）. Relevant indicators of liver function were not the risk factors for thyroid dysfunction（P>0.05）. Conclusion 19.4% of patients with chronic HCV hepatitis had abnormal thyroid function. It was significantly higher than the normal population. The level of liver function had no significant effect on the thyroid dysfunction.