摘要：目的 探究阻塞性睡眠呼吸暂停低通气综合征（obstructive sleep apnea hypoventilation syndrome ,OSAHS）与超敏C反应蛋白的相关性探究。方法 选取2011年4月至2013年5月在我院接受治疗的OSAHS的患者40例作为实验组，选取40名正常健康人为对照组。观察两组患者的超敏C反应蛋白的含量，以及互相之间的相关性。结果 两组患者经过检查后，实验组患者的每小时睡眠内呼吸暂停加上低通气的次数(AHI)为30.5±22.5次/小时,明显高于对照组患者的AHI（2.4±1.6次/小时)，实验组患者的最低血氧饱和度（70．5%±5.0%）明显低于对照组患者的最低血氧饱和度（97.5%±4.9%）。实验组患者的超敏C反应蛋白的水平(3.55±2.53mg/L)明显高于对照组患者的超敏C反应蛋白的水平（1.43±1.65mg/L)。两者差异具有统计学上有意义（P<0.05）。结论 对于OSAHS患者来说，超敏C反应蛋白的水平明显增高，且病情越重，其超敏C反应蛋白的水平水平越高，超敏C反应蛋白的水平能够反应OSAHS的病情严重程度，可以作为辅助诊断治疗因素。

Abstract: Objective To explore the correlation between obstructive sleep apnea hypoventilation syndrome (OSAHS) and hypersensitive C-reactive protein. Methods 40 cases of patients with obstructive sleep apnea hypoventilation syndrome 40 normal healthy controls were involved in this study. The hypersensitive C-reactive protein levels in patients and healthy controls were detected. Results The AHI times per hour in patients with OSAHS were significantly higher than that of healthy controls. The lowest oxygen saturation in patients was significantly lower than that of controls. The hypersensitive C-reactive protein levels in patients were significantly higher than control group (p < 0.05). Conclusion The hypersensitive C-reactive protein level could reflect severity of obstructive sleep apnea hypoventilation syndrome, and may be used as an index for auxiliary diagnosis and treatment of patients with OSAHS.