目的 探讨原发性甲状腺淋巴瘤(PTL)的18F- FDG PET/CT影像表现。
方法 回顾2009年11月至2013年8月淋巴瘤患者805例,病理证实PTL者12例,分析18F-FDG PET/CT图像特点,以及SUVmax 值及与临床指标相关性。
结果 PTL好发于中老年妇女,弥漫大B细胞淋巴瘤(DLBCL)及粘膜相关淋巴瘤(MALToma)常见。18F-FDG PET/CT 图像显示甲状腺双侧或单侧塑形增大,病灶密度弥漫性均匀性减低49.4±11.8HU,且代谢明显增高(SUVmax均值12.4±8.7),常伴占位效应及高代谢淋巴结。SUVmax值不受年龄、性别、B症状、分期影响(P>0.05),但与IPI评分具有相关性(P=0.018)。
结论 18F-FDG PET/CT显像有助于PTL的早期诊断。
Objective To analyze the imaging of 18F-FDG PET/CT scan for the patients with primary thyroid lymphoma (PTL). Methods Between November 2009 and August 2013, 12 patients with primary thyroid lymphoma (PTL) were histopathologically diagnosed in 805 lymphoma patients. 18F-FDG PET/CT scan was performed before any therapy. The imaging was analyzed in all patients with PTL. The relationship between clinic factors and SUVmax value was also evaluated. Results PTL developed mostly in middle-aged and older females. Diffuse large B-cell lymphoma (DLBCL) and Mucosal-associated lymphoid tissue lymphoma (MALToma) were major histological types of PTL. Unilateral or bilateral enlargements of thyroid were detected in 18F-FDG PET/CT imaging of all patients with PTL, with homogenous, hypodensity and hypermetabolic lesions (CT value, 49.4±11.8HU; SUVmax value, 12.4±8.7). SUVmax value of thyroid had no relevant with age, gender, B symptom, and stage (P>0.05), but had a relationship with IPI score (P=0.018). Conclusion 18F-FDG PET/CT imaging can help early diagnosis the patients with PTL.