目的 探讨CT引导下放射性粒子125I瘤内植入治疗腹膜后转移淋巴结的可行性、方法与近期疗效。方法 20例腹膜后淋巴结转移患者经CT引导下125I粒子瘤内植入，跟踪随访1～24个月观察近期疗效。结果 20例患者在CT引导下全部顺利完成粒子植入，未出现出血、感染等并发症。15例以腰疼症状为主的患者术后一周疼痛开始缓解，其中9例完全缓解，6例部分缓解；2例腰疼伴一侧下肢水肿患者淋巴结均有体积缩小。结论 CT引导下125I粒子植入治疗腹膜后转移淋巴结安全、微创、近期疗效满意，能有效控制局部症状。

Objective To investigate the efficacy and feasibility of CT guided 125I intratumoral implantation in the treatment of lymph node metastasis of retroperitoneal. Methods 20 cases of retroperitoneal lymph node metastasis patients were treated by CT guided 125I seeds implantation in tumor, followed up for 1-24 months to observe the near future curative effect. Results 20 patients were all successfully completed 125I seeds implantation under the guidance of CT without bleeding, infection and other complications. The back pain symptoms in 15 patients began to ease after one week treatment, of which 9 cases were complete remission and 6 patients were partial remission. The volume of lymph nodes of one side of lower extremity edema in 2 patients had reduction. Conclusion CT guided 125I seeds implantation is safe, minimally invasive and curative effect method in the treatment of retroperitoneal lymph node metastasis, and could effectively control the local symptoms.