目的 以世界卫生组织(WH0)推荐的标准作依据,检测深圳市一组处于甲状腺疾病治愈期孕妇在孕早期的尿碘水平,了解该孕妇群体妊娠期的碘营养状况。方法 连续收录160名甲状腺疾病治愈后成功妊娠的孕早期妇女作为本次研究对象,采用过氧乙酸四甲基苯胺氧化显色法检测尿液的碘含量。结果 该组孕妇尿碘浓度中位数为52.6μg/L,显著低于WHO孕妇的尿碘要求水平;处于碘缺乏状态的孕妇比率高达71.9%。结论 深圳市甲状腺疾病愈后孕妇孕早期的碘营养状况可能处于严重不足水平,尿碘在适宜范围内的人数仅占7.5%。呼吁加强对孕妇尿碘的监测。加强孕妇补碘知识的宣传与科普教育。
Objective Iodine deficiency is widely reported in China. However, data is slim in that early pregnancy with a history of thyroid diseases. This study was therefore conducted to assess the iodine nutrition in pregnant women, who were followed up for recovery from various kinds of thyroid diseases. Methods 160 women with previous thyroid diseases were consecutively recruited for early pregnancy without any treatment of medicine and a normal results of blood test of thyroid function, i.e. free thyroxin (FT4), thyrotropin (TSH), thyroglobulin (Tg), thyroglobulin antibody (Tg-Ab) and antimicrosomal antibody (TM-Ab). The urinary iodine (UI) were detected and assessed for testing the iodine nutrition status. Results The median urinary iodine (MUI) concentrations were found to be 52.6μg/L with a range of 14.2~561.3μg/L. Only 7.5% in the group was fond meeting up the WHO standard of >150μg/L. Conclusion The iodine status in pregnant women, who recovered from various kinds of thyroid diseases were fond under WHO standard for pregnant women to some serious degree, which calls for further research for the underline mechanism. Public education is also urgently needed for this population in Shenzhen.