目的 探讨血清睾酮（T）、硫酸脱氢表雄酮(DHEA-S) 水平在多囊卵巢综合征( PCOS)诊断中的价值。方法 采用化学发光法分别检测了年龄21～30岁41 例PCOS 患者血清T、DHEAS 的浓度, 并选择年龄21～30 岁50 例正常育龄期妇女作为对照。结果 PCOS 患者血清T、DHEA-S的水平明显较对照组高差异有显著性( P< 0. 05)；单项检测PCOS 患者血清T其敏感性为82.9%、特异性为86.0%；单项检测PCOS 患者血清DHEA-S其敏感性为75.6%、特异性为88.0%；合检测PCOS 患者血清T、DHEA-S其敏感性为92.7%、特异性为96.0%,其敏感性、特异性明显高于单项检测。结论 T、DHEAS联合检测可作为PCOS的诊断标准之一，值得推广和应用。

Objective To explore the value of combined detection of serum testosterone (T) with dehydroepiandrosterone sulfate (DHEA-S) in diagnosis of polycystic ovarian syndrome (PCOS). Methods The concentration of serum T and DHEA-S in 41 PCOS patients and 50 normal females between 21 and 30 years old were tested by chemiluminescence technique. Results There were significant difference on the serum levels of T and DHEA-S between PCOS patients and normal controls (P<0.05). The diagnosis sensitivity and specificity of PCOS patients by testing serum T level were 82.9% and 86.0%. The diagnosis sensitivity and specificity of PCOS patients by testing serum DHEA-S level were 75.6% and 88.0%. The diagnosis sensitivity and specificity of PCOS patients by combined detection of serum T and DHEA-S level were 92.7% and 96.0%. The diagnosis sensitivity and specificity of combined detection was obviously higher than that of single detection. Conclusion The combined detection of serum T and DHEAS could be used as one of diagnostic criteria of PCOS and worth for widely application.