目的 探讨老年分化型甲状腺癌淋巴结转移（LMDTC）的临床影响因素及131 I 治疗效果与非老年LMDTC的差异。方法 对38例LMDTC患者临床影响因素，并用B超、CT 、131 I显像及Tg变化判断131 I治疗效果差异。结果 老年组与非老年组LMDTC比较：淋巴结大小(P= 0.0452)及合并远处转移(P= 0.0126)；131 I治疗有效率老年组为64.7%（11/17），非老年组为95.2%（20/21），两组差异有统计学意义(P＜0.05)。随访期内未出现131 I治疗引起造血系统抑制、慢性涎腺炎和继发肿瘤的发生。结论 老年组与非老年LMDTC的临床影响因素有差异，131 I治疗效果不及非老年组，但仍为是有效且安全的治疗方法。

Objective To explore the difference of the main clinical influence factors and 131I therapeutic effect between the elderly and non-elderly patients with lymph node metastases from differentiated thyroid cancer (LMDTC). Methods The clinical influence factors in 38 patients with LMDTC were retrospectively analyzed. The difference of 131I therapeutic effect was assessed comprehensively by detection of neck ultrasonography and CT，whole body scan with 131I and changes of serum Tg level in elderly and non-elderly patient groups. Results There were significant differences in the size of lymph node and the incidence of metastases between the two groups (P＜0.05). The total effective rate of 131I therapy were 64.7% and 95.2% in the elderly group and the non-elderly group respectively (P<0.05). No hemopoietic system damage, chronic sialadenitis and secondary tumors caused by 131I therapy were found in the follow-up period．Conclusion There are some differences in the main clinical influence factors between two groups, and 131I therapeutic effect is less prominent in the elderly group than that in non-elderly group, but 131I therapy is still effective and safe for the elderly patients with LMDTC.