目的 探讨核素89Srcl2对骨转移瘤患者的治疗效果。方法 75例肿瘤患者经全身骨扫描显像证实存在多发性骨转移瘤，使用核素89Srcl2治疗后，通过统计分析比较治疗前后骨痛的缓解程度、外周血象的改变及骨转移灶变化情况。结果 核素89Srcl2治疗骨转移瘤疗效明确，75例患者中60例疼痛出现不同程度的缓解，缓解率达80%（P<0.01），其中19例患者疼痛完全消失；而治疗前后外周血象无明显改变；患者骨转移灶缓解率达89%（P<0.01）。结论 核素89Srcl2对骨转移瘤患者的止痛效果好，毒副反应小，且骨转移灶缓解率高，是一种有效的治疗手段。

Objective To investigate the therapeutic effects of strontium-89 therapy in patients with bone metastases. Methods Seventy-five cancer patients with multiple bone metastases confirmed with whole body bone scan imaging were treated with strontium-89. The catabolic effects of bone pain, the changes of peripheral hemogram and bone metastases lesions were analyzed before and after strontium-89 therapy. Results Among seventy-five cases of patients, sixty cases appeared different degree of pain relief, and the remission rate was 80% (P＜0.01); Nineteen patients pain disappeared completely. There was no significant change for peripheral hemogram during treatment period and the bone metastases remission rate in all cancer patients was 89% (P＜0.01). Conclusion Strontium-89 therapy is an effective therapeutic method for patients with bone metastases with favorable effects on relieving pain, low reaction of toxicity and high remission rate.