目的 了解全年龄段有消化道症状患者的幽门螺杆菌（Hp）感染情况。方法 选取本院门诊及住院有慢性上腹疼痛、反复上消化道出血等消化道症状的患者共2275例，年龄2~88岁，男1058例，女1217例。采用13C-尿素呼气试验的检测方法，分析幽门螺杆菌感染的检测结果。结果 2275例患者中，13C-尿素呼气试验阳性者928例，占40.79%。男性患者，阳性414例，占39.13%；女性患者，阳性514例，占42.23%，女性高于男性（P <0.01)。各全年龄段中，以31~45岁年龄组幽门螺杆菌感染率为最高，阳性333例，占48.40%。成人各年龄段与15岁以下年龄组相比，HP感染率差异有统计学意义，（P <0.01)。结论 对31~45岁年龄段的人群应给予关注，同时应通过健康教育提高人们的相关知识水平，有针对性地开展Hp筛查，早诊断、早治疗，从而有效预防和控制胃部疾病的发生。

Objective To explore the situation of Helicobacter Pylori infection in the all age group of patients with gastrointestinal symptoms. Methods A total of 2275 outpatients and inpatients in our hospital with the gastrointestinal symptoms including chronic upper abdominal pain and hemorrhage were collected. 1058 males and 1217 females, aged from 2 to 88 years old (mean 40.25±19.79) were received 13C–Urea breath test (13C–UBT) in Suzhou Municipal Hospital. The 13C–UBT results were analyzed to detect the incidence of helicobacter pylori infection. Results According to the results of 13C –UBT test, 40.77% were HP positive in all these 2275 patients, while 39.13% were positive in the 1058 male cases, 42.23% were positive in the 1217 female cases. The 13C–UBT levels were significantly higher in females than that of males (P < 0.01). Among all age groups, patients at 31~45 years old group had highest rate of HP infection (48.40%). Compare to under 15 years old group, adults group have higher rate of HP infection (p<0.01). Conclusion Patients at 31~45 years old group have highest rate of HP infection. It is necessary for us to focus on these patients. Education should be strengthened in order to increase people’s knowledge of HP infection. Early diagnosis and treatment will effectively prevent and control the gastrointestinal disease.