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临床研究

恶性肿瘤的90Y玻璃微球瘤内注射治疗及其临床效果观察

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  • 天津市人民医院肿瘤科,天津 300121
朱慧(1984—),女,硕士,主治医师,主要从事肿瘤临床工作。Tel:13820855826;E-mail: zhuhui5826@163.com

收稿日期: 2013-11-26

  修回日期: 2014-07-21

  网络出版日期: 2014-09-03

Clinic Observation of Malignant Tumors Treated with Intervention of 90Y Glass Microspheres

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  • Department of Cancer, The people’s hospital of Tianjin, Tianjin 300121, China

Received date: 2013-11-26

  Revised date: 2014-07-21

  Online published: 2014-09-03

摘要

目的 探讨90Y-玻璃微球介入治疗晚期恶性肿瘤的疗效。方法 共18例恶性肿瘤病人,其中肝癌6例,肺癌5例,颈部淋巴结转移癌5例,上颌窦癌1例,肺癌胸壁转移1例,均经病理诊断证实。采取直接注入或者利用B超和CT引导下将90Y-玻璃微球引入肿瘤组织。结果 18例肿瘤中,完全消失(CR)为2例,部分缩小(PR)为9例,肿瘤稳定(SD)为6例,肿瘤进展(PD)为1例。14例病人可见疼痛减轻,4例疼痛未见明显缓解。结论 本方法可在晚期恶性肿瘤治疗上发挥重要作用,有较大临床应用前景。

本文引用格式

朱 慧,李佳丽,朱 卫,牛静秀,应简子,庞 雁 . 恶性肿瘤的90Y玻璃微球瘤内注射治疗及其临床效果观察[J]. 标记免疫分析与临床, 2014 , 21(4) : 364 . DOI: 10.11748/bjmy.issn.1006-1703.2014.04.003

Abstract

Objective To explore the therapeutic effect of malignant cancer treated with intervention of 90Y-lasbelled glass microspheres. Methods 18 cancer patients with primary tumor located in liver (6 cases), lung (5 cases), cervical lymph node metastases (5 cases), maxillary sinus carcinoma (1 case) and chest wall metastasis (1 case) were included in the study. All patients were confirmed by pathological diagnosis. 90Y-lasbelled glass microspheres was injected with or without the help of type-B ultrasonic and CT. Results Out of 18 cases of patients, 2 cases were CR, 9 cases were PR, 6 cases were SD and one case was PD. 14 cases were showed pain relief and the other 4 cases were no significant relief of pain. Conclusion This method is effective in the therapy of malignant cancer, and it has great potential for clinical application.
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