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临床研究

北京某地区2005至2012年献血人群中肝炎病毒感染情况分析

  • WANG Hai-bao ,
  • ZHU Li-guo ,
  • WANG De-qing
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  • 1. 解放军总医院输血科,北京 100853;2.南开大学医学院,天津 300071
王海宝(1971—),男,副主任技师,临床输血与输血免疫方向。E-mail:wanghb9839@sina.com

网络出版日期: 2013-11-01

基金资助

军队“十二五”重大专项课题(AWS11J007-08)

Analysis on Transfusion-transmitted Hepatitis Viruses Infection of Volunteer Blood Donors During 2005 to 2012 in Beijing Area

  • 王海宝1,朱立国1,2,汪德清1
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  • Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China

Online published: 2013-11-01

摘要

目的 了解北京市某地区无偿献血者中肝炎病毒(HBV、HCV)的感染情况。 方法 收集2005至2012年在我院无偿献血人群的血液标本165566份,用ELISA方法检测HBsAg和抗-HCV在血清中的阳性情况,并进行统计学分析。 结果 在165566份样本中,有1936人次为肝炎病毒感染者,总感染率为1.17%,其中HBV感染率为0.71%, HCV感染率为0.46%,混合感染率为0.006%。感染者中,男女比例为7.9:1,年龄中以36~45岁为最高(1.42%)。 结论 该地区的献血人群中肝炎病毒感染率呈逐年上升趋势,应加强输血传播的控制,保证输血安全。

本文引用格式

WANG Hai-bao , ZHU Li-guo , WANG De-qing . 北京某地区2005至2012年献血人群中肝炎病毒感染情况分析[J]. 标记免疫分析与临床, 2013 , 20(5) : 291 -305 . DOI: 10.11748/bjmy.issn.1006-1703.2013.05.004

Abstract

Objective To explore the transfusion-transmitted hepatitis viruses (HBV and HCV) infection of volunteer blood donations in Beijing area. Methods 165566 plasma samples from volunteer blood donors in our hospital since January 2005 to December 2012 were collected. Enzyme-linked immunosorbent assay (ELISA) was used for detecting HBsAg and anti-HCV in serums and the results were analyzed by SPSS software. Results There 1936 blood donors were transfusion-transmitted hepatitis viruses infected in 165566 and the total infected rate was 1.17%. Among them, the infection rate of HBV, HCV, and mixed infection was 0.71%, 0.46% and 0.006%, respectively. The ratio of males to females in infected blood donors was 7.9:1. The infected rate of in age 35 to 45 group was the highest (1.42%). Conclusion The incidence of transfusion-transmitted hepatitis viruses infection has a increase trend and would enhance regulation in transfusion-transmission to ensure the safety of blood transfusion.
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