Objective To explore the changes of blood rheology in teenage patients with fatty liver. Methods The hemorheology in 80 cases of 7-18 years old teenage with fatty live were analyzed by using blood rheometer LG- R-80A. Results The average whole blood viscosity, plasma viscosity, erythrocyte aggregation index in fatty liver teenage were significantly higher than that in normal group (P <0.01). Conclusion The teenage with fatty liver have the obvious hemorheological abnormal which is wealth to pay attention.